Projects to deliver Mental Health Catalyst 1.0

Mental Health Catalyst 1.0 is a four-year programme commissioned by Wellcome to accelerate the development, translation and uptake of new and better interventions for conditions associated with depressed mood.
Evidence synthesis and pathway mapping: building the foundation for new and better interventions

Clinically significant depressed mood remains one of the most pressing challenges in global mental health. Although scientific understanding has advanced substantially, progress in translating research into interventions that deliver sustained impact at scale has been uneven and slow.
Announcement, 24 March 2026

The University of Cambridge has launched a major new initiative designed to accelerate the pace of innovation in interventions for conditions associated with clinically significant depressed mood.